| GENE INFORMATION | ||
|---|---|---|
| Gene name | EPHX2 |
|
| Description | Epoxide hydrolase 2 | |
| Gene type | Protein coding gene | |
| Chromosome | 8 | |
| Cytoband | p21 | |
| Chromosome location(bp) | 27490781 - 27545564 | |
| Ensembl | ENSG00000120915 | |
| UniProt | P34913 | |
| PROTEIN FUNCTIONi |
|---|
| EPHX2 is a bifunctional enzyme whose C-terminal domain exhibits epoxide hydrolase activity. It metabolizes both xenobiotic and physiological epoxides, degrading potentially toxic compounds while regulating steady-state levels of endogenous signaling mediators. This dual role positions EPHX2 as a key player in detoxification pathways and homeostasis of bioactive epoxide molecules. |
NOTE: Gene expression values are scaled by log2(TPM+0.001).