| GENE INFORMATION | ||
|---|---|---|
| Gene name | CYP4F3 |
|
| Description | Cytochrome P450 family 4 subfamily F member 3 | |
| Gene type | Protein coding gene | |
| Chromosome | 19 | |
| Cytoband | p13.12 | |
| Chromosome location(bp) | 15640897 - 15662825 | |
| Ensembl | ENSG00000186529 | |
| UniProt | Q08477 | |
| PROTEIN FUNCTIONi |
|---|
| CYP4F3 is a cytochrome P450 monooxygenase that metabolizes endogenous fatty acids and oxylipins through NADPH/O₂-dependent ω-hydroxylation. It contributes to the resolution of inflammation by inactivating both pro-inflammatory and anti-inflammatory oxylipins, serving as a broad modulator of lipid mediator homeostasis. |
NOTE: Gene expression values are scaled by log2(TPM+0.001).