| GENE INFORMATION | ||
|---|---|---|
| Gene name | CYP2E1 |
|
| Description | Cytochrome P450 family 2 subfamily E member 1 | |
| Gene type | Protein coding gene | |
| Chromosome | 10 | |
| Cytoband | q26.3 | |
| Chromosome location(bp) | 133520406 - 133561220 | |
| Ensembl | ENSG00000130649 | |
| UniProt | P05181 | |
| PROTEIN FUNCTIONi |
|---|
| CYP2E1 catalyzes NADPH/O₂-dependent ω-1 hydroxylation of fatty acids, with highest activity toward saturated fatty acids. It may also contribute to xenobiotic metabolism (probable). This enzyme plays a role in both endogenous fatty acid oxidation and potential detoxification pathways. |
NOTE: Gene expression values are scaled by log2(TPM+0.001).