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CYP2C19 catalyzes NADPH/O₂-dependent hydroxylation and epoxidation of PUFAs, primarily at the ω-1 position.
It also metabolizes plant monoterpenes (e.g., converting limonene to carveol/perillyl alcohol) and is a key enzyme
in the oxidation of diverse drugs, including anticonvulsants (S-mephenytoin), proton pump inhibitors (omeprazole),
antifungals (fenbendazole), and antidepressants (citalopram, imipramine). This multifunctional enzyme bridges
endogenous lipid metabolism and xenobiotic detoxification.
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